Differentiate among the types of stimuli to which receptors respond. While most sensory neurons respond best to stimuli of a single sensory modality (e.g., mechanical or thermal), nociceptors can often be activated by stimuli … Mechanical nociceptors respond to excess pressure or mechanical deformation. •Nociceptors can be very long neurons. This response, known as nociception, consists of the emission of pain signals to the central nervous system, that is, to the brain and spinal cord.
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